Deterministic Lateral Displacement as a Means to Enrich

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Deterministic Lateral Displacement as a Means to Enrich ...

Request PDF Deterministic Lateral Displacement as a Means to Enrich Large Cells for Tissue Engineering The enrichment or isolation of selected cell types from

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Improved pillar shape for deterministic lateral ...

Jan 01, 2017  Deterministic lateral displacement as a means to enrich large cells for tissue engineering Anal. Chem. , 81 ( 2009 ) , pp. 9178 - 9182 CrossRef View Record in Scopus

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Deterministic Lateral Displacement: The

a highly parallel deterministic lateral displacement (DLD) device incorporating diamond microposts and moving into processing, for the first time, apheresis blood

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Particle Separation Using Deterministic Lateral Displacement

Deterministic lateral displacement Works by using the mechanism of laminar flow past an array of posts. The array of posts divide the flow into several different

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Gravity driven deterministic lateral displacement for ...

Aug 16, 2016  Deterministic lateral displacement (DLD) is a popular separation method in microfluidics that can effectively fractionate a polydisperse suspension of particles by

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Deterministic displacement of particles and oil droplets ...

Nov 15, 2018  Deterministic lateral displacement as a means to enrich large cells for tissue engineering Anal. Chem. , 81 ( 21 ) ( 2009 ) , pp. 9178 - 9182 CrossRef View Record in

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(PDF) Centrifugal deterministic lateral displacement ...

Green JV, Radisic M, Murthy SK (2009) Deterministic Lateral Displacement as a Means to Enrich Large Cells for Tissue Engineering. Anal Chem 81:9178–9182. doi:

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Nanoscale lateral displacement arrays for the separation ...

Aug 01, 2016  Deterministic lateral displacement (DLD) pillar arrays are an efficient technology to sort, separate and enrich micrometre-scale particles, which include parasites 1, bacteria 2,

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Microfluidic Isolation and Enrichment of Nanoparticles

In this review article, we survey microfluidic methods for nanoparticle isolation and enrichment based on their underlying mechanisms, including acoustofluidics, dielectrophoresis, filtration, deterministic lateral displacement, inertial microfluidics, optofluidics, electrophoresis, and affinity-based methods.

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Electrokinetically driven deterministic lateral ...

Nov 29, 2014  Green JV, Radisic M, Murthy SK (2009) Deterministic lateral displacement as a means to enrich large cells for tissue engineering. Anal Chem 81:9178–9182. Article Google Scholar Herrmann J, Karweit M, Drazer G (2009) Separation of suspended particles in microfluidic systems by directional locking in periodic fields.

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Deterministic displacement of particles and oil droplets ...

Nov 15, 2018  Deterministic lateral displacement as a means to enrich large cells for tissue engineering Anal. Chem. , 81 ( 21 ) ( 2009 ) , pp. 9178 - 9182

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Microfluidic Separation of Blood Components through ...

Deterministic lateral displacement (DLD) is an emerging technique for separating particles based on size in a microfluidic environment. This technique shows great promise as a means to continuously separate particles smaller than the feature size of a microfluidic array. As can be appreciated, particles ideally travel one of two types of

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Measuring the Effectiveness of Three Dimensional ...

improve upon prior techniques and optimize efficiency and accuracy in separation. 2.3 Two Dimensional Determin-istic Lateral Displacement The most basic form of deterministic lateral displacement implements two ranges of motion along the x-axis and y-axis. The main focus of the separation technique is to create equivalent migration paths using ...

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Deterministic separation of suspended particles in a ...

Oct 07, 2015  Deterministic lateral displacement (DLD) is a fractionation technique that can be implemented in all active, passive and hybrid modes. ... Green J V, Radisic M and Murthy S K 2009 Deterministic lateral displacement as a means to enrich large cells for tissue engineering Anal. Chem. 81 9178–82.

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Effects of the particle deformability on the critical ...

Deterministic lateral displacement (DLD) technology is a newly developed method which can separate microscale and nanoscale particles continuously and efficiently. In this paper, a direct numerical simulation method (i.e. a fictitious domain method) is used to simulate the motion of an elastic particle (modelled as homogeneously elastic body ...

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Purification of complex samples: Implementation of a ...

Deterministic lateral displacement (DLD) is efficiently implemented as a size-based fractionation technique to separate two populations of particles around a specific size. However, real biological samples contain components of many different sizes and a single DLD separation step is not sufficient to purify these complex samples.

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Purification of complex samples: Implementation of a ...

May 16, 2018  Green JV, Radisic M, Murthy SK. Deterministic Lateral Displacement as a Means to Enrich Large Cells for Tissue Engineering. Anal Chem. 2009;81: 9178–9182. pmid:19810716 . View Article PubMed/NCBI Google Scholar 19.

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Cell Sorting Using Electrokinetic Deterministic Lateral ...

We show that by combining deterministic lateral displacement (DLD) with electrokinetics, it is possible to sort cells based on differences in their membrane and/or internal structures. Using heat to deactivate cells, which change their viability and structure, we then demonstrate sorting of a mixture of viable and non-viable cells for two different cell types.

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Deterministic Lateral Displacement: The Next-Generation ...

Jan 23, 2018  Processing via deterministic lateral displacement (DLD) removes more platelets as compared to Ficoll in parallel leukapheresis samples. (A) Scatterplot showing range of normal donor platelet and white blood cell (WBC) cell counts used in this study. Mean counts: 152.4×10 3 /µL WBC and 2.61×10 6 /µL platelets (+). (B) A typical 24-h-old ...

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Deterministic lateral displacement for particle separation ...

Abstract. Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow with a resolution of down to 10 nm. For 10 years, DLD has been extensively studied, employed and modified by researchers in terms of theory, design, microfabrication and application to develop newer ...

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Asymmetrical Deterministic Lateral Displacement Gaps for ...

Green J. V., Radisic M. Murthy S. K. Deterministic lateral displacement as a means to enrich large cells for tissue engineering. Anal. Chem. 81, 9178–9182 (2009). Loutherback K. et al. . Deterministic separation of cancer cells from blood at 10 ml/min. AIP Adv. 2, 042107 (2012). [PMC free article]

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Microfluidic Separation of Blood Components through ...

Deterministic lateral displacement (DLD) is an emerging technique for separating particles based on size in a microfluidic environment. This technique shows great promise as a means to continuously separate particles smaller than the feature size of a microfluidic array. As can be appreciated, particles ideally travel one of two types of

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Deterministic separation of suspended particles in a ...

Oct 07, 2015  Deterministic lateral displacement (DLD) is a fractionation technique that can be implemented in all active, passive and hybrid modes. ... Green J V, Radisic M and Murthy S K 2009 Deterministic lateral displacement as a means to enrich large cells for tissue engineering Anal. Chem. 81 9178–82.

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UBLISHING JOURNAL OF MICROMECHANICS AND

Scaling deterministic lateral displacement arrays for high throughput and dilution-free enrichment of leukocytes David W Inglis1, Megan Lord2 and Robert E Nordon2 1 Department of Physics and Astronomy, Macquarie University, NSW 2109 Australia 2 Graduate School of Biomedical Engineering, University of New South Wales, NSW 2052 Australia

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Combining DC and AC electric field with s Deterministic ...

30 Deterministic Lateral Displacement (DLD) 3–5. is one of such microfluidic sorting techniques. This method separates 31 particles in the range of icrommetres based on size in a continuous flow. DLD devices consist of a microchannel within 32 which there is an array of micro-posts.

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Three-dimensional electrodes for dielectrophoretic ...

Deterministic lateral displacement uses shifted rows of posts in a microfluidic labyrinth to sort particles based on their size. The principle uses the deterministic behavior of particles in the device, particles below a certain size move straight through the device, while larger particles are displaced to the side.

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Separation of parasites from human blood using ...

Feb 18, 2011  Deterministic lateral displacement as a means to enrich large cells for tissue engineering. Green JV, Radisic M, Murthy SK. Anal Chem, 81(21):9178-9182, 01 Nov 2009 Cited by: 29 articles PMID: 19810716

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Deformability of red blood cells affects their velocity in ...

Keywords: Deterministic Lateral Displacement, Red Blood Cells, Deformability, Particle Separation 1. Introduction Malaria is one of the deadliest infectious diseases accounting for about one million death cases every year (Nayyar et al., 2012). It is therefore of paramount importance to improve the efficiency of disease prevention,

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Deterministic separation of suspended particles in a ...

Oct 07, 2015  We use a macromodel of a flow-driven deterministic lateral displacement microfluidic system to investigate conditions leading to size-separation of suspended particles. This model

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Purification of complex samples: Implementation of a ...

Deterministic lateral displacement (DLD) is efficiently implemented as a size-based fractionation technique to separate two populations of particles around a specific size. However, real biological samples contain components of many different sizes and a single DLD separation step is not sufficient to purify these complex samples.

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Deterministic fractionation of binary suspensions moving ...

Jan 11, 2014  Deterministic lateral displacement as a means to enrich large cells for tissue engineering Green, JV; Radisic, M; Murthy, SK A theoretical analysis of the resolution due to diffusion and size dispersion of particles in deterministic lateral displacement devices

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